The C-D bonds are slightly stronger than C-H. When this bond breaks at the rate-limiting step, the overall speed slows down because C-D cleavage costs more energy. This is a positive isotopic effect.
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The C-D bonds are slightly stronger than C-H. When this bond breaks at the rate-limiting step, the overall speed slows down because C-D cleavage costs more energy. This is a positive isotopic effect. |