Depto. Química Orgánica

PREPARATION OF ACYL HALIDES

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15/07/2017
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The chlorides are the most useful and easiest to prepare of the all the possible acyl halides.
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Click here to recall the mechanism of this reaction.
Fluorides
Acyl chlorides and anhydrides are the starting materials to obtain acyl fluorides, extremely reactive and quite dangerous to handle.
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Bromides
Acyl bromides are obtained by addition-elimination of phosphorous tribromide on a carboxylic acid.
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Iodides
Acyl iodides are obtained by reaction of iodine and red phosphorous (PI3 formed in situ) with a carboxylic acid.
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