Donald James Cram (1919-2001)

American chemist, professor at the University of California, Los Angeles (UCLA) from 1947. In 1952 he formulated Cram’s rule, the first model for predicting the stereochemistry of nucleophilic addition to carbonyl compounds with an α stereocentre, and later the chelate model.

He received the 1987 Nobel Prize in Chemistry, with Jean-Marie Lehn and Charles Pedersen, for the development of host–guest chemistry (molecular recognition).

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