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qorganica.es qorganica.comAdvanced Organic Chemistry Course map Español

Problems and exercisesAspirin

Exercise 1

Why is the Kolbe–Schmitt carboxylation carried out with sodium phenoxide and not with phenol? What changes with potassium phenoxide at higher temperature?

Exercise 2

Write the mechanism of the Hock reaction (rearrangement of cumyl hydroperoxide in acid) and say which group migrates.

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