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qorganica.es qorganica.comAdvanced Organic Chemistry Course map Español

Problems and exercisesIbuprofen

Exercise 1

In the Boots route, the step from 4-isobutylacetophenone to the homologous aldehyde uses the Darzens condensation. Write its stages and say what kind of retrosynthetic operation it represents.

Exercise 2

Ibuprofen is sold as the racemate. What method from this course would allow (S)-ibuprofen to be obtained? Propose one resolution method and one asymmetric method.

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