Problems and exercisesIbuprofen
Exercise 1
In the Boots route, the step from 4-isobutylacetophenone to the homologous aldehyde uses the Darzens condensation. Write its stages and say what kind of retrosynthetic operation it represents.
Exercise 2
Ibuprofen is sold as the racemate. What method from this course would allow (S)-ibuprofen to be obtained? Propose one resolution method and one asymmetric method.