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qorganica.es qorganica.comAdvanced Organic Chemistry Course map Español

Problems and exercisesRetrosynthesis

Exercise 1

Propose a retrosynthesis of 2-phenylbutan-2-ol leading to starting materials of two carbons or fewer plus benzene. How many reasonable C–C disconnections does the alcohol carbon have?

Exercise 2

Why is isobutylbenzene not disconnected into benzene and 1-chloro-2-methylpropane? What product would that Friedel–Crafts alkylation give?

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