Problems and exercisesAlkylation of ketones and carboxylic acid derivatives
Exercise 1
Propose how to prepare 2-benzylcyclohexanone, and ethyl 2-methylpropanoate bearing an allyl group on C2, from simple carbonyl compounds.
Exercise 2
Why does the attempt to prepare 2-tert-butylcyclohexanone by treating the lithium enolate of cyclohexanone with tert-butyl chloride fail? What is obtained?
Exercise 3
In the manganese-catalysed alkylation of acetophenone with ethanol, which intermediates are formed? What is the by-product?