Problems and exercisesγ-Alkylation of 1,3-dicarbonyl compounds
Exercise 1
Write the products of acetylacetone (2,4-pentanedione) with: (a) 1 eq. of NaH, then benzyl bromide; (b) 2 eq. of NaNH2 in liquid NH3, benzyl bromide, then H3O+.
Exercise 2
Why does the dianion react at the γ carbon and not at α, the most acidic carbon?