Problems and exercisesRobinson annulation
Exercise 1
Write the product of the Robinson annulation of 2-methylcyclohexanone with methyl vinyl ketone under basic conditions. Why is the new ring formed on the carbon bearing the methyl group?
Exercise 2
Why is its precursor 4-(diethylamino)butan-2-one, or the corresponding quaternary ammonium salt, often used instead of methyl vinyl ketone?