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Problems and exercisesCross-coupling reactions

Exercise 1

Which coupling would you choose to attach a phenyl group to C4 of ethyl 4-iodobenzoate: Kumada, Negishi or Suzuki? Justify your answer.

Exercise 2

1-Bromo-4-chlorobenzene is treated with one equivalent of phenylboronic acid, Pd(PPh3)4 and Na2CO3. What product is formed? Explain.

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