Problems and exercisesCross-coupling reactions
Exercise 1
Which coupling would you choose to attach a phenyl group to C4 of ethyl 4-iodobenzoate: Kumada, Negishi or Suzuki? Justify your answer.
Exercise 2
1-Bromo-4-chlorobenzene is treated with one equivalent of phenylboronic acid, Pd(PPh3)4 and Na2CO3. What product is formed? Explain.