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Rearrangement Reactions

Amides ('with D') give amines ('with N') by reactions where the alkyl group changes positions by rearrangement.

Hofmann rearrangement of a primary amide: RCONH₂ + Br₂ + 4 NaOH gives R–NH₂, Na₂CO₃, 2 NaBr and 2 H₂O

The mechanism of the reaction is pretty complicated and will be seen elsewhere.

But click here if you are curious!