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Reactivity

The main reactions of amines are:

Double Hofmann degradation of 1,2-dimethylpiperidine: methylation with MeI, Ag₂O and heat open the ring; a second sequence gives 1,5-hexadiene

Hofmann Degradation

 Animation of the orbitals of the ketone carbonyl group

Carbonyl Addition

 Formation of the nitrosyl cation from sodium nitrite and HCl and its attack by a tertiary amine to give the N-nitrosoammonium salt

Nitrosation