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Problems and exercisesSynthesis Strategies

1. Synthesis from benzene

Propose a synthetic sequence for the following compounds, using benzene as the only aromatic precursor:

Four compounds: cyclohexyl 4-isopropylphenyl ketone, m-bromonitrobenzene, 2-bromo-6-chlorotoluene and 6-chloro-1,1,3,3-tetramethylindan-5-amine

2. Order matters

Propose syntheses of m-chloronitrobenzene and p-chloronitrobenzene from benzene.

3. Diazonium salts

How would you prepare 1,3,5-tribromobenzene from aniline?

See the solutions →